Nausea, diarrhea and weight loss were the most common adverse events recorded in patients in the four trials, but they were generally mild to moderate in intensity and generally occurred in the first weeks of treatment.
This content should not be used during a medical emergency or for the diagnosis or treatment of any medical condition.
The uniformity of the results is really encouraging and gives us great hope that our faith in roflumilast has been confirmed.
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There was also a statistically significant difference with roflumilast in other prespecified endpoints, including median time to first exacerbation (moderate to severe in the salmeterol study, and mild, moderate and severe in the tiotropium study) and in
* Calcium Interactions: It is important to talk with your doctor or pharmacist about possible interactions between your over-the-counter and prescription medications, and calcium supplements. For example, calcium supplements may reduce the absorption of t
* Exercise, which not only improves your bone health, but increases muscle strength, coordination and balance.
Roflumilast represents the first in a new class of agents to treat COPD and, if approved, would be the first oral anti-inflammatory maintenance treatment for the disease.
Based on the results from the pivotal studies published this week, it appears that roflumilast provides added activity on top of other commonly used treatments for COPD,
Nycomed is a privately owned global pharmaceutical company with a differentiated portfolio focused on branded medicines in gastroenterology, respiratory and inflammatory diseases, pain, osteoporosis and tissue management.
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