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When added to standard bronchodilator therapies in the two six-month studies, a clear trend for the reduction of exacerbations was observed with roflumilast, over and above what was achieved with these therapies alone.
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The results of the two six-months trials examining the additive effect of roflumilast on top of salmeterol or tiotropium support and extend the findings of the 12-month trials, by showing a clinically relevant lung function improvement in patients with i
Orlistat, the active ingredient in alli, is the most-studied weight loss medicine, with safety established through 100 clinical studies involving more than 30 thousand patients."
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Roflumilast could be an important new treatment for COPD, Breathing becomes severely compromised and patients may need to be admitted to a hospital.
It reduced exacerbations, or lung attacks, and significantly improved lung function, in a patient population whose lung function is very poor.
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Dialysis patients whose blood was not monitored for warfarin levels after they received the drug had the highest risk of stroke (almost three-fold higher than patients not on warfarin).
However, almost no studies have examined whether warfarin can also prevent stroke in atrial fibrillation patients who are also on dialysis.
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